Saturday, June 30, 2018

Herpes and the Brain

As with everything else, there are trends in scientific research. Concepts like sustainability blossomed with climate change, and studies of the human microbiome exploded a decade ago.

The same can be said about disease research, driven by the number of diseases, both noncommunicable and infectious, that are currently lacking effective treatments options. It is easy to see "finding a cure" as the main goal of disease research, but that future-focused vision excludes individuals suffering in the present. A common trend in disease research now is long-term effects of disease, as in, what will happen when we are exposed to such pathogens or experience a disease for an extended period of time? Additionally, how do one-off infections change our health down the road, after the symptoms have come and gone?

Image borrowed from https://alzheimersdiseasebiol2095.wordpress.com/

It is especially interesting when pathogens overlap or influence noncommunicable diseases, as seen  with HPV and cancer, just to name one example. Recently, a relationship between specific Human Herpes Virus (HHV) strains (6A and 7) and Alzheimer's disease was "accidentally" discovered by researchers at Mt. Sinai's Icahn School of Medicine. Twice as much HHV was detected in brain tissue from individuals with Alzheimer's compared to brain tissue of those without Alzheimer's.

Although a direct link isn't clear, this is still an interesting finding. Yet, not a surprising one...

HHV-6 is a neurotropic virus, meaning it can invade nervous system. There are many viruses that are neurotropic, so it would be interesting to see if any of the others, like Japanese encephalitis virus, polio, and rabies (just to name a few) have similar influence on chronic disease down the road.

Image from Mayo Clinic Foundation for Medical Education and Research

HHV-6 is often acquired at a young age, producing a non-specific febrile illness and a rash, called "roseola". HHV-6 is spread through saliva droplets, similar to how a cold or flu are spread, so it is easy to imagine how so many young children acquire the infection. For many, the symptoms can look a lot like a seasonal flu infection with a rash, but it can also cause febrile seizures, encephalitis or intractable seizures. Many also suspect symptoms of chronic fatigue and extreme malaise.

The interesting thing about many herpes viruses is that after the initial infection, which may or may not cause symptoms, the virus experiences a period of latency, where it hides in a specific type of cell, before reactivation later in life. The type of cell that supports latency of the virus depends on the type of herpes virus, as they all have their own favorite. Some prefer nervous system cells, whereas others prefer cells of the immune system. According to Bjørn Grinde, HHV-6 prefers leukocytes, which play a large roll in inflammatory pathways and immune system function. Leukocytes can be trafficked across the blood brain barrier and into the central nervous system, which may be the way latent HHV-6A found its way into the brains of the Alzheimer's disease study at Mt. Sinai.

HHV-7 is also considered a roseola virus and causes similar symptoms in infants. HHV-7 prefers T-cells for latency (also according to Bjørn Grinde's paper... I am not a herpes researcher!), which are also critical cells for immune response. Similarly to HHV-6A, T-cells can cross the blood brain barrier, which may expose the central nervous system to latent HHV-7 virus.

Regardless of the molecular methods used, these viruses may contribute to the activation or progression of Alzheimer's disease. Pretty interesting!

12 comments:

  1. Hey thanks for this amazing post. Would love to read more of such blogs. You can also have a look at Thailand Visa On Arrival Form for more information.

    ReplyDelete
    Replies
    1. Am Laura Mildred by name, i was diagnosed with Herpes 4 years ago i lived in pain with the knowledge that i wasn't going to ever be well again i contacted so many herbal doctors on this issue and wasted a large sum of money but my condition never got better i was determined to get my life back so one day i saw Mr. Morrison Hansen post on how Dr. Emu saved him from Herpes with herbal medicine i contacted Dr. Emu on his Email: Emutemple@gmail.com we spoke on the issue i told him all that i went through and he told me not to worry that everything will be fine again so he prepared the medicine and send it to me and told me how to use it, after 14 days of usage I went to see the doctor for test,then the result was negative, am the happiest woman on earth now thanks to Dr. Emu God bless you. Email him at: Emutemple@gmail.com Call or Whats-app him: +2347012841542 

      Delete
  2. This comment has been removed by the author.

    ReplyDelete
  3. Hey thanks for this amazing post. Would love to read more of such blogs. You can also have a look at flight ticket booking for more information.

    ReplyDelete
  4. Hey thanks for this amazing post. Would love to read more of such blogs. You can also have a look at Singapore Visa Online for more information.

    ReplyDelete
  5. Hello, Good Day Everyone, I'm Charley from US and I'm here to testify the good work of Dr Oseghale,
    He helped me cure my Herpes with his Harbal Medication,I was cured in 2weeks for those of you that need his help on any diseases,HIV/AID ETC Contact via whatsapp +2347062814871

    ReplyDelete
  6. Hi Friends i am so glad to writing this article today to tell the world how Dr vadi cured my HSV VIRUS,i have been detected with HSV-1 AND HSV-2 since five years ago, ever since then my life has been in complete bizarre and agony,i have used so many drugs that was prescribed to me by several doctors,but it didn't cure my HSV VIRUS neither did it reduce the pain,until a certain i was checking for solution in the internet,then miraculously came across Dr vadi the powerful herbalist that cure numerous individuals HSV-1 AND HSV-2 INFECTION,then i contacted his whatsApp number at +2348074133083  or email: doctorvadi@yahoo.com i explained everything to him and prepared a cure that cure my HSV-1 AND HSV-2 disease totally after receiving his herbal medicine, so my friends viewers why wait and be suffer when there is someone like Dr vadi that can cure any disease HIV/ CANCER/ HEPATITIS B VIRUS, you can contact his via : doctorvadi@yahoo.com or WHATSAPP+2348074133083    

    ReplyDelete
  7. I am really happy that i have been cured from (HERPES SIMPLEX VIRUS) with the herbal medicine of Dr OGBENI , i have been suffering from this disease for the past 3 years and 4 mouth without solution until i came across the email of this doctor who have cure so many people with his herbal medicine, i also choose to give him a chance to help me and my husband, he told me what to do and i kindly did it, and he gave us his herbal medicine and direct me on how to use it, i also follow his instructions for use and he ask us to go for a check up after 1 week and 5days which i did, to my greatest surprise our result came out as negative, we are really happy that there is someone like this doctor who is ready to help anytime any day. To all the readers and viewers that is doubting this testimony stop doubting it and contact this doctor if you really have one and see if he will not actually help you. i am not a stupid woman that i will come out to the public and start saying what someone have not done for me and i know that there are some people out there who are really suffering and hurting their family just because of these diseases so you can Email him on dr.ogbeniherbalhome@gmail.com OR
    WHATSAPP him on +2348103170329

    Thank you for your time and be happy again

    https://www.facebook.com/Dr-Ogbeni-100937351577518/

    ReplyDelete
  8. This is the interesting thing that you shared above and also interested to read more such information. I always love to read about various aspect of the information.
    Wackyfreaky tech update
    Wackyfreaky lifestyle update
    Wackyfreaky business update
    Wackyfreaky education update
    Wackyfreaky health update

    ReplyDelete
  9. Do You Need A Powerful Africa Native Doctor? I Mean A Spiritual Herbalist
    With Great Spirit Connected To Ancestors. Call or WhatsApp +2349058774809 Dr Obodubu Monday Is A High Voodoo Priest Master. He is a Spell Caster, Native
    Doctor, Spiritual Herbalist, Powerful Sickle cell Healer, Spiritual
    Astrologer, Psychic Reader, Multi Guru, Witch Doctor, Priest Of Africa
    Money Ritual.
    Have You Been To Native Doctor to Native Doctor Without Any Solution To
    Your Problems Or Rather Add To it? Have You Been To Place To Place In View
    Of A Powerful Native Doctor That Can Solve All Your Predicament, You Must
    Understand That There Is A Native Doctor That Supersede All Native Doctor
    Among All Native Doctor, If You Are In Search Of A Powerful Native Doctor
    With Great Spiritual Powers, Then You Must Be In Search Of A Native Doctor
    That Derives Power From The Marine World. That Is The Spirituality Of The
    Greatest Africa Native Doctor Obodubu.
    Dr Obodubu Is Recognized All Over The World Of Marine Kingdom, As One
    Of The Top Fortunate And Most Powerful Native Doctor Of Charms Casts From
    The Beginning Of His Ancestors ship Until Now Dr who lives Strong
    Among All Other Native Doctors, There Have Never Been Any Form Of
    Impossibility Beyond The Control Of Dr Obodubu. It Doesn't Matter The
    Distance Of The Person With The Problems Or Situation, All You Have To Do
    Is Believe
    In The Native Obodubu charms Casts That Works, He Always
    Warns Never To Get His Charms Casts If You Do Not Believe Or Unable To
    Follow His Instruction.
    It Is The Assignment Of The Native Doctor Obodubu To Offer
    Services To Those In Need Of Spiritual Assistance Not Minding The Gravity
    Of Your Situations Or Distance As Long As Water, Sea, Ocean, Lake, River
    Sand etc. Are Near You, Then Your Problems Of Life Would Be Controlled
    Under Your Foot.
    If You Need Any Spiritual Help On Any of These:
    Get Your Lover Back
    Fruit Of The Womb
    Fibroid
    Business Boom
    Financial Breakthrough
    Get Rich Without Ritual WhatsApp +2349058774809
    Do As I Say
    Bad Dream
    Promise And Fail
    Epilepsy
    Spiritual Attack
    Land/Court Case
    Mental Disorder
    Political Appointment
    Visa Approval
    Cancer
    Examination Success
    Spend And Get Back
    Good Luck
    Natural Health
    Hypertension
    Diabesity (Diabetic+Obesity
    Stroke
    Sickle Cell
    Impotency
    Win Court Case
    Promotion At Work
    Commanding Tone
    Protection Ring
    Marriage Success
    Love Ring
    Favour Ring
    Recover Lost Glory
    Spiritual Power For Men Of God
    Travel Success Ring
    Job Success
    Lotto/Pool Win And Many More.
    Make Haste To Call or WhatsApp Dr Obodubu Monday +2349058774809. Or Mail Him to
    babadoctorobodubuspiritualhome@gmail.com For Spiritual Problem Today And
    You Will Surely
    Get Solution To All Your Predicament.
    Email: babadoctorobodubuspiritualhome@gmail.com

    ReplyDelete
  10. I now own a business of my own with the help of Elegantloanfirm with a loan of $900,000.00 USD. at 2% rate charges, at first i taught with was all a joke until my loan request was  process under five working days and my requested funds was transfer to me. am now a proud owner of a large business with 15 staffs working under me. All thanks to the loan officer Russ Harry he is a God sent, you can contact them to improve your business on.. email-- Elegantloanfirm@hotmail.com. / Whatsapp number +393511617486

    ReplyDelete
  11. HOW I GOT MY DESIRED LOAN AMOUNT FROM A RELIABLE AND TRUSTED LOAN COMPANY LAST WEEK Email for immediate response: drbenjaminfinance@gmail.com Call/Text: +1(646)820-1981 Whatsapp +19292227023 Visit their website and believe yourself Company Website: https://capitalmanage-inc.com/

    Hello everyone, My name is Mr.Justin Riley Johnson, I'm from Texas, United State, I'm here to testify of how i got my loan from CAPITAL MANAGEMENTS INC (drbenjaminfinance@gmail.com) after i applied Two times from various loan lenders who claimed to be lenders right here this forum,i thought their lending where real and i applied but they never gave me loan until a friend of mine introduce me to {Dr.Benjamin Scarlet Owen} the C.E.O of CAPITAL MANAGEMENTS INC who promised to help me with a loan of my desire and he really did as he promised without any form of delay, I never thought there are still reliable loan lenders until i met {Dr.Benjamin Scarlet Owen}, who really helped me with my loan and changed my life for the better. I don't know if you are in need of an urgent loan also, So feel free to contact Dr.Benjamin Scarlet Owen on his email address: drbenjaminfinance@gmail.com CAPITAL MANAGEMENTS INC holds all of the information about how to obtain money quickly and
    painlessly via Whatsapp +19292227023 Email: drbenjaminfinance@gmail.com

    And consider all your financial problems tackled and solved. Share this to help a soul right now, Thanks
    Visit their website and believe yourself Company Website:https://capitalmanage-inc.com/

    ReplyDelete